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[Syndrome of chronic intravascular coagulation in the course of chronic myeloid leukemia]
Z Rusinowska1, B Stella-Hołowiecka
1I Kliniki Chorób Wewnetrznych Sl. Ak. Med. w Katowicach.
Insights
Chronic intravascular coagulation is common in leukemia but often missed. Two chronic myeloid leukemia cases show varied treatment needs, from managing the underlying disease to transfusions and anticoagulants.
Area of Science:
- Hematology
- Oncology
Background:
- Chronic intravascular coagulation (CIC) is a frequent complication of malignancies, particularly leukemias.
- Diagnosis of CIC in the context of hematologic malignancies can be challenging.
Observation:
- Two cases of CIC associated with chronic myeloid leukemia (CML) are presented.
- One patient was in the chronic phase of CML, while the other was in the blastic phase.
Findings:
- The patient in the chronic phase required only treatment of the underlying CML.
- The patient in the blastic phase needed treatment for the blastic crisis, along with heparin, platelet mass, and frozen plasma transfusions.
Implications:
- This highlights the variable clinical presentation and management of CIC in CML.
- Timely diagnosis and tailored treatment strategies are crucial for improving outcomes in these patients.
Abstract:
The syndrome of chronic intravascular coagulation occurs very often in the course of malignancies including leukaemias, however, it is not always diagnosed. Two cases are presented of chronic syndrome of intravascular coagulation in the course of chronic myeloid leukaemia; in one patient being in chronic phase and in other patient during blastic phase. In the first case the patient required only causative treatment of the basic disease, in the second case, apart from causative treatment of blastic phase, heparin administration, platelet mass and frozen plasma transfusion were necessary.