Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A universal, multi-modality localization system for animal radiosurgery

T D Solberg1, A A De Salles, D Hovda

  • 1Jonsson Comprehensive Cancer Center, Los Angeles, CA, USA.

Acta Neurochirurgica. Supplement
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of Receiver Operating Curve Analysis and Machine Learning With an Independent Dose Calculation System Reduces the Number of Physical Dose Measurements Required for Patient-Specific Quality Assurance.

International journal of radiation oncology, biology, physics·2020
Same author

Absorption of wireless radiation in the child versus adult brain and eye from cell phone conversation or virtual reality.

Environmental research·2018
Same author

A mathematical framework for virtual IMRT QA using machine learning.

Medical physics·2016
Same author

Dosimetric characterization of an image-guided stereotactic small animal irradiator.

Physics in medicine and biology·2011
Same author

An x-ray image guidance system for small animal stereotactic irradiation.

Physics in medicine and biology·2010
Same author

Nonconvulsive seizures after traumatic brain injury are associated with hippocampal atrophy.

Neurology·2010
Same journal

Microneurosurgical Training on Simulators: The Zurich Microsurgery Lab Experience.

Acta neurochirurgica. Supplement·2025
Same journal

Educational Impact of an Annotation System Integrated with an Exoscope for Cerebral Aneurysm Surgery: Case Description.

Acta neurochirurgica. Supplement·2025
Same journal

Artificial Intelligence and Augmented Reality in Vascular Neurosurgery.

Acta neurochirurgica. Supplement·2025
Same journal

Experiences with and Practical Implications of Using a Hybrid Operating Room.

Acta neurochirurgica. Supplement·2025
Same journal

Epidemiology and Aetiology of Cerebral Cavernous Malformations.

Acta neurochirurgica. Supplement·2025
Same journal

Novel Hemodynamic Parameters for Cerebral Ischemia in Patients with Occlusive Cerebrovascular Disease Using Dual ASL Perfusion Imaging.

Acta neurochirurgica. Supplement·2025
See all related articles

A new stereotactic localization system enables radiosurgery in animal models. This adaptable system uses specialized fixation adapters for various animals, allowing precise radiation delivery comparable to human procedures.

Area of Science:

  • Neurosurgery
  • Medical Imaging
  • Radiation Oncology

Background:

  • Stereotactic radiosurgery offers precise tumor targeting.
  • Animal models are crucial for preclinical research in neurosurgery and oncology.
  • Existing stereotactic systems may lack adaptability for diverse animal models.

Purpose of the Study:

  • To develop and validate a versatile stereotactic localization system for radiosurgery in multiple animal models.
  • To enable precise image-guided radiation delivery in preclinical research.
  • To bridge the gap between human and animal stereotactic procedures.

Main Methods:

  • Designed animal-specific fixation adapters compatible with a Brown-Roberts-Wells (BRW) head ring.
  • Utilized CT, MRI, PET, and angiographic imaging-compatible materials for adapters.

Related Experiment Videos

  • Integrated the system for radiographic localization, treatment planning, and radiation delivery.

    • Main Results:

    • Successfully developed a stereotactic localization system applicable to various animal models.
    • Demonstrated compatibility with multiple imaging modalities (CT, MRI, PET, angiography).
    • Enabled stereotactic radiosurgery procedures analogous to human clinical practice.

    Conclusions:

    • The developed stereotactic system provides a standardized and adaptable platform for preclinical radiosurgery research.
    • Facilitates accurate and reproducible image-guided radiation delivery in animal models.
    • Enhances the translational value of animal studies for human neurosurgical and oncological treatments.