Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary intrahepatic stones

M H Kim1, J Sekijima, S P Lee

  • 1Department of Medicine, University of Washington School of Medicine, USA.

The American Journal of Gastroenterology
|April 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Randomized Phase III Trial of Anthracyclines Followed by Taxane versus Taxane Plus Carboplatin as (Neo)Adjuvant Therapy in Patients with Triple-Negative Breast Cancer: KCSG BR 15-1 PEARLY Trial.

Annals of oncology : official journal of the European Society for Medical Oncology·2026
Same author

A prospective study for brain metastasis imaging screening in patients with advanced HER2-positive or triple-negative breast cancer.

ESMO open·2026
Same author

A randomized phase III clinical trial of weekly versus tri-weekly cisplatin-based chemoradiotherapy for locally advanced cervical cancer: results of the TACO (GCIG/KGOG 1027/THAI 2012) study.

ESMO open·2026
Same author

Black Hole Spectroscopy and Tests of General Relativity with GW250114.

Physical review letters·2026
Same author

Computerised tomography (CT)-like images based on T1-weighted gradient echo magnetic resonance imaging (MRI) sequences for the assessment of osteochondral lesions of the ankle.

Clinical radiology·2026
Same author

GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.

Physical review letters·2025
Same journal

Calendar of Courses, Symposiums and Conferences.

The American journal of gastroenterology·2026
Same journal

Molecular Nonendoscopic Tests for the Early Detection of Esophageal Squamous Carcinoma and High-Grade Dysplasia: Promising Progress.

The American journal of gastroenterology·2026
Same journal

ACG Clinical Guideline: Colonic Diverticulitis.

The American journal of gastroenterology·2026
Same journal

Continuing Medical Education Questions: July 2026.

The American journal of gastroenterology·2026
Same journal

Continuing Medical Education Questions: July 2026.

The American journal of gastroenterology·2026
Same journal

2026 CME Information.

The American journal of gastroenterology·2026
See all related articles

Hepatolithiasis, or primary intrahepatic stones, are stones formed within the liver, distinct from those originating outside. Management of this condition has evolved with modern interventional and surgical techniques.

Area of Science:

  • Gastroenterology and Hepatology
  • Surgical Pathology

Background:

  • Hepatolithiasis, or primary intrahepatic stones, is common in the Far East, previously known as Oriental cholangiohepatitis.
  • These stones, primarily calcium bilirubinate but increasingly cholesterol-rich, form within the liver (de novo).
  • They differ from extrahepatic stones in etiology, composition, and clinical progression.

Purpose of the Study:

  • To differentiate primary intrahepatic stones from extrahepatic stones.
  • To highlight the unique pathogenetic etiology, chemical composition, and clinical course of hepatolithiasis.
  • To discuss the evolving management strategies for hepatolithiasis.

Main Methods:

  • Review of clinical presentations and diagnostic findings associated with hepatolithiasis.

Related Experiment Videos

  • Analysis of the chemical composition of primary intrahepatic stones.
  • Evaluation of advancements in interventional radiology, cholangioscopy, and surgical techniques.

    • Main Results:

    • Primary intrahepatic stones are characterized by unique pathogenetic factors and composition.
    • Patients often experience recurrent cholangitis, liver abscesses, and hepatic destruction.
    • Recent recognition of intrahepatic stones with high cholesterol purity.

    Conclusions:

    • Hepatolithiasis presents a distinct clinical syndrome with significant hepatic morbidity.
    • Modern interventional and surgical innovations have improved patient management.
    • Understanding the unique aspects of primary intrahepatic stones is crucial for effective treatment.