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Determination of normal human fetal immunoglobulin M levels
D J Vick1, W A Hogge, D E Normansell
1Department of Obstetrics & Gynecology, University of Virginia Health Sciences Center, Charlottesville.
Clinical and Diagnostic Laboratory Immunology
|January 1, 1995
Abstract:
Immunoglobulin M (IgM) levels were measured in 198 cord blood samples from 192 apparently normal pregnancies from 24 weeks of gestation to term. Simple linear regression analysis yielded a standard curve for IgM development during pregnancy showing a 0.5 mg/dl increase in IgM per week of gestation. This curve allows the comparison of fetal IgM levels from pregnancies considered to be at risk for intrauterine infection.