Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clinical capillary electrophoresis

J P Landers1

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic/Foundation, Rochester, MN 55905, USA.

Clinical Chemistry
|April 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A rotationally-driven dynamic solid phase sodium bisulfite conversion disc for forensic epigenetic sample preparation.

Lab on a chip·2023
Same author

DNA purification using dynamic solid-phase extraction on a rotationally-driven polyethylene-terephthalate microdevice.

Analytica chimica acta·2016
Same author

DNA Extraction on Microfluidic Devices.

Forensic science review·2015
Same author

Sample-to-Result STR Genotyping Systems: Potential and Status.

Forensic science review·2015
Same author

A universal concept for stacking neutral analytes in micellar capillary electrophoresis.

Analytical chemistry·2011
Same author

A score card for evaluating physical education programs for physically handicapped children.

Research quarterly·2010

Capillary electrophoresis offers automated, rapid, and high-efficiency separations for clinical laboratories. This versatile analytical technique can analyze diverse analytes, from small ions to large biomolecules, impacting routine and specialized testing.

Area of Science:

  • Analytical Chemistry
  • Clinical Diagnostics
  • Biochemistry

Background:

  • Capillary electrophoresis (CE) is an emerging analytical technique with significant potential in clinical laboratories.
  • Its high-efficiency separations offer advantages over traditional labor-intensive methods like gel electrophoresis.
  • CE is versatile, capable of analyzing a wide range of analytes, including small ions, proteins, and DNA.

Purpose of the Study:

  • To introduce clinical scientists to the principles and instrumentation of capillary electrophoresis.
  • To review current research on the application of CE in clinical laboratory settings.
  • To highlight the potential of CE as a replacement or complement to existing analytical methods.

Main Methods:

  • Review of scientific literature focusing on capillary electrophoresis applications in clinical diagnostics.

Related Experiment Videos

  • Discussion of the fundamental principles and instrumentation of CE.
  • Analysis of CE's performance characteristics for various clinical analytes.

    • Main Results:

    • Capillary electrophoresis provides automated, rapid, and high-efficiency separations.
    • The technique demonstrates versatility in analyzing diverse analytes, from small molecules to macromolecules.
    • CE shows promise for both routine and esoteric clinical analyses, complementing techniques like HPLC.

    Conclusions:

    • Capillary electrophoresis is a valuable and versatile tool for the modern clinical laboratory.
    • Its adoption can enhance efficiency and expand analytical capabilities for a broad spectrum of tests.
    • Further research and implementation of CE are encouraged for clinical applications.