Screening and sequence determination of a cDNA encoding the human brain 4-aminobutyrate aminotransferase
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1Department of Biochemistry, University of Tennessee, Knoxville 37996-0840, USA.
Gene
|April 3, 1995
Abstract:
A human brain cDNA library constructed in the lambda ZAP II vector was screened using a fragment of pig brain cDNA encoding 4-aminobutyrate aminotransferase (pGaba-t). A cDNA that encodes the human brain Gaba-t (hGaba-t) has been isolated from the library and sequenced. Using the GenBank and EMBL databases, comparison of the predicted amino-acid sequence of hGaba-t with the pig enzyme revealed 95.4% homology.