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A novel pituitary transcription factor is produced by alternative splicing of the human GHF-1/PIT-1 gene
M Delhase1, V Vila, E L Hooghe-Peters
1Pharmacology Department, Medical School, Free University of Brussels (V.U.B.), Belgium.
Gene
|April 3, 1995
Abstract:
An alternative splice acceptor site in intron 1 of the human GHF-1/PIT-1 gene was sequenced. The use of this splice site is responsible for a 78-bp in-frame insertion upstream from exon 2 and leads to the hGHF-2/PIT-2 cDNA detected in normal human pituitary.