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Cloning of a canine cDNA homologous to the human transforming growth factor-beta 1-encoding gene
A M Manning1, J A Auchampach, R F Drong
1Upjohn Laboratories, Kalamazoo, MI 49001, USA.
Gene
|April 3, 1995
Abstract:
A 1369-bp cDNA that encodes a homolog of the human transforming growth factor-beta 1 (TGF-beta 1) has been isolated from canine endothelial cells using a combination of PCR and traditional plaque-screening methods. The deduced 390-amino-acid sequence of the canine TGF-beta 1 precursor has 91-94% identity to those deduced from the previously described human and mouse TGF-beta 1 clones.