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Plasma somatostatin levels in ulcerative colitis
11st Department of Internal Medicine, Comenius University, Bratislava, Slovak Republic.
Hepato-Gastroenterology
|December 1, 1994
Abstract:
The circadian (24 hour) rhythmicity of somatostatin in healthy subjects and patients with ulcerative colitis (UC) was studied and established. UC patients were found to have a higher 24-hour amplitude, a higher average level and a longer peak level phase of plasma somatostatin. This finding may indicate a defensive role of somatostatin in inflammatory bowel disease.