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Systemic mastocytosis associated with chronic myelomonocytic leukemia: clinical features and response to interferon
1Department of Dermatology, Centre Hospitalier Victor Dupouy, Argenteuil, France.
Journal of the American Academy of Dermatology
|May 1, 1995
Abstract:
Systemic mastocytosis is a rare disease that shows marked heterogeneity in clinical manifestations and prognosis. It may be associated with hematologic disorders. We describe a patient with systemic mastocytosis associated with chronic myelomonocytic leukemia accompanied by ascites, pleural effusion, and development of skin lesions along a surgical scar. The disease responded well to interferon alfa therapy. This is the second report of successful treatment of mastocytosis with interferon alfa and the first associated with a hematologic malignancy.