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[Acanthamoeba keratitis. Apropos of 2 cases]
D P Bezeaud1, P A Renard, J L Couderc
1Fondation Ophtalmologique Adolphe de Rothschild, Paris.
Journal Francais D'Ophtalmologie
|January 1, 1994
Summary
Acanthamoeba keratitis, a rare eye infection, is increasing in France, particularly in soft contact lens wearers. Prompt diagnosis and treatment with propamidine and antibiotics can lead to recovery, though some damage may persist.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Parasitology
Background:
- Acanthamoeba keratitis (AK) is a rare but severe corneal infection.
- Increasing incidence of AK reported in France, particularly among soft contact lens users.
- Early diagnosis and treatment are crucial for visual outcomes.
Observation:
- Two new cases of AK in young patients using soft hydrophilic contact lenses.
- One patient adhered to disinfection protocols, while the other did not.
- Clinical presentation strongly suggested AK, confirmed by parasitological analysis of corneal samples.
Findings:
- Successful treatment achieved using a combination of propamidine and antibiotic eye drops.
- Both patients recovered, but one experienced significant anatomical damage requiring a penetrating corneal graft.
- The study highlights the potential severity of AK even with appropriate treatment.
Implications:
- Emphasizes the importance of proper contact lens hygiene to prevent AK.
- Suggests that even with adherence to guidelines, AK remains a risk for contact lens wearers.
- Underscores the need for heightened clinical suspicion and rapid diagnostic confirmation of AK.