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Age at menarche and nutritional supplementation

A D Khan1, D G Schroeder, R Martorell

  • 1Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853-6301, USA.

The Journal of Nutrition
|April 1, 1995
PubMed
Summary

Childhood nutritional supplements, Atole and Fresco, did not significantly alter age at menarche in Guatemalan girls. However, year of birth and socioeconomic status influenced menarche timing.

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Area of Science:

  • Nutritional Epidemiology
  • Human Growth and Development
  • Public Health Nutrition

Background:

  • Early life nutrition is crucial for pubertal development.
  • Studies have investigated the impact of nutritional supplements on age at menarche.
  • Guatemalan children were exposed to either high-energy, high-protein (Atole) or low-energy, no-protein (Fresco) supplements.

Purpose of the Study:

  • To determine if childhood exposure to Atole or Fresco supplements affects age at menarche.
  • To examine the association of year of birth and socioeconomic status (SES) with age at menarche.
  • To explore potential interactions between supplement type, SES, and year of birth.

Main Methods:

  • Retrospective data collection from 832 Guatemalans aged 15-30 years.
  • Comparison of mean age at menarche between Atole and Fresco groups.
  • Analysis of immigrant data (n=144) not exposed to supplements.
  • Statistical analysis to assess the influence of year of birth, SES, and supplement type.

Main Results:

  • Mean age at menarche was similar in the Atole (13.75 ± 1.22 years) and Fresco (13.74 ± 1.36 years) groups.
  • Age at menarche for unexposed immigrants was 13.55 ± 1.20 years.
  • Age at menarche declined by 0.69 years over the study period, and was earlier in higher SES households.
  • Significant positive interactions were observed between supplement type and SES, and between supplement type and year of birth.

Conclusions:

  • Childhood exposure to Atole or Fresco supplements did not significantly alter age at menarche.
  • Year of birth and socioeconomic status are significant factors influencing age at menarche.
  • Further research is needed to explain the observed interactions between supplement type, SES, and year of birth.

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