Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Encephalomyelopathy in young cats

A C Palmer1, J B Cavanagh

  • 1Wellcome Laboratory for Comparative Neurology, School of Veterinary Medicine, Cambridge, London.

The Journal of Small Animal Practice
|February 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corticosterone and serotonin similarly influence GABAergic and purinergic pathways to affect cortical inhibitory networks.

Journal of neuroendocrinology·2018
Same author

Sex differences in the early life correlates of natural antibody concentrations.

Journal of developmental origins of health and disease·2015
Same author

History of One Health and One Medicine.

The Veterinary record·2014
Same author

THE PROLAPSE SYNDROME.

British medical journal·2010
Same author

Two Cases of Rupture of Vagina during Labour.

Proceedings of the Royal Society of Medicine·2009
Same author

A Case in which over 3 ft. of Small Intestine were dragged out through a Perforation in the Uterus.

Proceedings of the Royal Society of Medicine·2009
Same journal

Predictive utility of computed tomography-derived renal parenchymal volume for long-term postoperative renal function in cats with hydronephrosis.

The Journal of small animal practice·2026
Same journal

The Animal Trauma Triage Score outperforms the VetCOT score in cats with high-rise syndrome.

The Journal of small animal practice·2026
Same journal

Maine Coons and intestinal intussusception: breed predisposition and clinicopathological features.

The Journal of small animal practice·2026
Same journal

A case of successful surgical management of colonic duplication with pygomelia in a 2-month-old dog.

The Journal of small animal practice·2026
Same journal

Clinical outcomes of lateral ear canal resection performed in routine clinical practice for chronic otitis externa in dogs: a retrospective descriptive study of 58 ears (2016-2025).

The Journal of small animal practice·2026
Same journal

Accuracy and agreement of a wearable device for heart rate and oxygen saturation monitoring in awake dogs.

The Journal of small animal practice·2026
See all related articles

Neurological disease in young cats caused significant hindleg paralysis and vision defects. Histopathology revealed Wallerian degeneration and neuronal loss, suggesting an infectious etiology.

Area of Science:

  • Veterinary Neurology
  • Feline Pathology

Background:

  • Neurological disorders in cats can lead to severe motor and sensory deficits.
  • Affected animals were young (3-16 months), housed in research colonies or referred from practice.
  • High incidence in litters (over 40%) indicates a significant economic impact.

Purpose of the Study:

  • To characterize the clinical and pathological findings of a neurological disease in young cats.
  • To investigate the potential cause of the observed neurological signs.

Main Methods:

  • Clinical examination of 19 affected cats.
  • Histopathological analysis of spinal cord, brain stem, and cerebral white matter.
  • Examination of cerebellar Purkinje cells and spinal cord neurons.

Related Experiment Videos

Main Results:

  • Cats presented with hindleg paralysis, head shaking, nystagmus, vision defects, and reduced proprioception.
  • Widespread Wallerian degeneration was observed in the spinal cord and brain.
  • Neuronal loss (Purkinje cells, spinal cord) and accompanying gliosis were noted in multiple cases.

Conclusions:

  • The clinical presentation and pathological findings suggest an infectious cause for this feline neurological disease.
  • While no viral agent was isolated, the pattern is consistent with known infectious neurological conditions in cats.
  • Further investigation is warranted to identify the causative agent and prevent commercial losses.