Fat tissue: relationship between chemical shift and magnetization transfer

The middle calves of the legs of 25 volunteers (12 men and 13 women, aged 18-25 years), as well as phantoms, were examined with 1.5-T magnetic resonance imaging. Gradient-recalled technique was combined with magnetization transfer contrast (MTC) and chemical shift imaging. Periodic oscillation of the MTC effect in fat tissue with variation of echo time was identified at the frequency corresponding to the water-fat chemical shift difference.