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Updated: Aug 16, 2026

Intraductal Injection of LPS as a Mouse Model of Mastitis: Signaling Visualized via an NF-κB Reporter Transgenic
Published on: September 4, 2012
[Pathogenic studies of Escherichia coli mastitis]
E N Noordhuizen-Stassen1, W D Kremer, J A Lohuis
1Vakgroep Bedrijfsdiergeneeskunde en Voortplanting, Faculteit Diergeneeskunde, Utrecht.
Abstract:
In this paper research about the pathogenesis of Escherichia coli mastitis, executed by the Department of Herd Health and Reproduction, is reviewed. The use of experimental infection models to study the systemic clinical symptoms of an Escherichia coli mastitis and the effect of anti-inflammatory drugs on this symptoms are described. Additionally, correlations between pre-infection in vitro leucocyte function tests and the severity of an Escherichia coli infection are discussed. Finally, some future developments and their possible applications are revealed.
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