Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Radioiodine-associated thyroid cancers

S Tezelman1, R F Grossman, A E Siperstein

  • 1Surgical Service, University of California-San Francisco/Mount Zion Medical Center 94115, USA.

World Journal of Surgery
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Etiological diagnosis of pneumonia: A goal worth pursuing?

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses·2012
Same author

Concentrations of krypton-85 near the Nevada Test Site.

Environmental science & technology·2012
Same author

Out-patient management of patients with chronic obstructive lung disease.

Canadian family physician Medecin de famille canadien·2011
Same author

Impact of total versus subtotal thyroidectomy on calcium metabolism and bone mineral density in premenopausal women.

The Journal of laryngology and otology·2008
Same author

Management of chronic bronchitis and acute exacerbations of chronic bronchitis.

International journal of antimicrobial agents·2008
Same author

Invasion of metastatic human follicular thyroid cancer is inhibited via antagonism of protein kinase C.

Cancer letters·2008

Radioactive iodine (131I) therapy for Graves' disease and toxic nodular goiter may be linked to thyroid cancer development. This study reviewed cases and literature, finding a potential association between 131I exposure and subsequent thyroid neoplasms.

Area of Science:

  • Endocrinology
  • Oncology
  • Nuclear Medicine

Background:

  • External radiation is a known risk factor for thyroid neoplasms.
  • The link between radioactive iodine (131I) and thyroid cancer remains controversial.

Purpose of the Study:

  • To investigate the association between radioactive iodine (131I) therapy and thyroid cancer development.
  • To analyze personal experience and existing literature on 131I-induced thyroid cancer.

Main Methods:

  • Retrospective review of patients treated with 131I for benign thyroid conditions.
  • Meta-analysis of previously reported cases from 1957 to the present.
  • Analysis of patient demographics, 131I dosage, latent period, and diagnostic methods.

Main Results:

Related Experiment Videos

  • Seven of 373 thyroid cancer patients (1.9%) had a history of 131I treatment.
  • Literature review identified 65 additional cases.
  • Mean age at 131I treatment was 45 years, with a mean latent period of 11.4 years.
  • Fine-needle aspiration cytology was positive for cancer in 86% of the study's patients.

Conclusions:

  • The findings suggest a potential association between radioactive iodine (131I) therapy and the development of thyroid cancer.
  • Further research is warranted to clarify the risks and establish causality.
  • Early detection through fine-needle aspiration cytology is crucial for patients with a history of 131I exposure.