Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postprandial hypotension in elderly patients with unexplained syncope

R W Jansen1, C M Connelly, M M Kelley-Gagnon

  • 1Hebrew Rehabilitation Center for Aged, Beth Israel Hospital, Boston, Mass, USA.

Archives of Internal Medicine
|May 8, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis.

bioRxiv : the preprint server for biology·2024
Same author

Anaesthetic management of a parturient with uncorrected tetralogy of Fallot undergoing caesarean section.

International journal of obstetric anesthesia·2014
Same author

Early discontinuation of treatment in patients with orthostatic hypotension.

Autonomic neuroscience : basic & clinical·2013
Same author

Glucagon and GLP-1 inhibit food intake and increase c-fos expression in similar appetite regulating centres in the brainstem and amygdala.

International journal of obesity (2005)·2013
Same author

Testing clinical surveillance of acute flaccid paralysis in Egypt post-eradication of poliomyelitis.

Tropical medicine & international health : TM & IH·2010
Same author

Cerebrovascular hemodynamics, gait, and falls in an elderly population: MOBILIZE Boston Study.

Neurology·2010

Postprandial hypotension, a drop in blood pressure after eating, is a key cause of unexplained syncope in older adults. This condition involves a failure to maintain systemic vascular resistance, likely due to splanchnic blood pooling.

Area of Science:

  • Gerontology
  • Cardiovascular Physiology
  • Clinical Medicine

Background:

  • Syncope in the elderly often has unclear causes, though hypotension is a possibility.
  • Postprandial hypotension is a prevalent blood pressure regulation disorder in older individuals.

Purpose of the Study:

  • To investigate the mechanisms behind postprandial hypotension.
  • To determine the role of postprandial hypotension in elderly patients experiencing unexplained syncope.

Main Methods:

  • Studied 16 elderly patients with unexplained syncope and 9 elderly controls.
  • Measured blood pressure, heart rate, vascular resistance, norepinephrine levels, and blood volumes before and after a meal.

Main Results:

  • Eight syncope patients exhibited postprandial hypotension, with a significant drop in mean arterial blood pressure post-meal.

Related Experiment Videos

  • Patients with postprandial hypotension showed a decrease in systemic vascular resistance, unlike controls.
  • Splanchnic blood volume increased in patients with postprandial hypotension and controls, but not in syncope patients without it.

    • Conclusions:

    • Postprandial hypotension is a significant factor in unexplained syncope among the elderly.
    • Evaluating syncope in older adults should include post-meal blood pressure monitoring.
    • Elderly patients with syncope and postprandial hypotension struggle to maintain systemic vascular resistance due to splanchnic blood pooling.