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Synthesis of some thiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones as potential platelet aggregation inhibitors
B Tozkoparan1, H Akgün, M Ertan
1Hacettepe University, Faculty of Pharmacy, Dept. of Pharmaceutical Chemistry, Ankara, Turkey.
Archiv Der Pharmazie
|February 1, 1995
Abstract:
Twenty new compounds having 2-methyl-6-benzylidenethiazolo[3,2-b]- 1,2,4-triazole-5(6H)-one (2a-d) and 2-methyl-6-(alpha-aminobenzyl)thiazolo-[3,2-b]-1,2,4- triazole-5-ol (5-20) structures were synthesized. Their structures were confirmed by elemental and spectroscopic analysis and their platelet aggregation inhibitory activities were investigated.