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[Mixed cryoglobulinemia associated with hepatitis C virus]
A De Diego Lorenzo1, R Bañares Cañizares, C González-Asanza
1Servicio de Aparato Digestivo, Hospital General Universitario, Gregorio Marañón, Madrid.
Revista Espanola De Enfermedades Digestivas
|January 1, 1995
Abstract:
We report six cases of essential mixed cryoglobulinemia associated with chronic liver disease and positive HCV markers, who showed several acute symptoms of vasculitis, arthralgias, neuropathy and glomerulonephritis. The presence in the serum and cryoprecipitates of anti HCV antibodies detected by the second-generation ELISA (ELISA 2) and the of HCV RNA by PCR in the serum in all six cases, suggest an important role for this virus in the pathogenesis of mixed cryoglobulinemia.