Related Experiment Videos
Periodic angioedema with eosinophilia: increased serum level of interleukin 5
1First Department of Internal Medicine, School of Medicine, Shinshu University, Matsumoto.
Internal Medicine (Tokyo, Japan)
|February 1, 1995
Abstract:
A 48-year-old man developed episodic non pitting edema and eosinophilia. Symptoms were alleviated promptly when treated with prednisolone. However, major basic protein (MBP), eosinophil cationic protein (ECP), and eosinophil-derived neurotoxin (EDN) levels in the serum as well as the total number of eosinophils remained high. During periods of attack serum levels of interleukin-5 (IL-5) were elevated, but the levels were lowered following treatment, suggesting that IL-5 is involved in periodic angioedema with eosinophilia.