Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Comparing standardized mortality ratios

B G Armstrong1

  • 1School of Occupational Health, McGill University, Montreal, Quebec, Canada.

Annals of Epidemiology
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of mortality with high temperatures in a temperate climate: England and Wales.

Journal of epidemiology and community health·2010
Same author

Exposure-response relationship between lung cancer and polycyclic aromatic hydrocarbons (PAHs).

Occupational and environmental medicine·2009
Same author

Estimating reduction in occupational disease burden following reduction in exposure.

Occupational and environmental medicine·2007
Same author

The effect of temperature on food poisoning: a time-series analysis of salmonellosis in ten European countries.

Epidemiology and infection·2004
Same author

Mortality and temperature in Sofia and London.

Journal of epidemiology and community health·2003
Same author

The combination of effects on lung cancer of cigarette smoking and exposure in quebec chrysotile miners and millers.

The Annals of occupational hygiene·2002
Same journal

Contribution of lifestyle factors to sex differences in educational inequalities in life expectancy in selected European countries.

Annals of epidemiology·2026
Same journal

What remains quantitative in quantitative intersectionality?

Annals of epidemiology·2026
Same journal

Revisiting the role of interaction effects in quantitative intersectionality research.

Annals of epidemiology·2026
Same journal

GLP-1 receptor agonist medications for weight loss: Sociodemographic patterns of awareness, use, and access in a U.S. national cohort.

Annals of epidemiology·2026
Same journal

Even low levels of physical activity are associated with lower all-cause mortality: A cohort study of 594,000 US adults.

Annals of epidemiology·2026
Same journal

Comment on "Distinct differences between COVID-19 vaccine refusers and vaccine hesitant in the United States: Results from a population-based survey and latent class analysis".

Annals of epidemiology·2026
See all related articles

The ratio of standardized mortality ratios (SMRs) offers greater precision than internal estimates but may introduce bias. Its enhanced precision relies on differing expected death distributions between cohorts, impacting bias-variance trade-offs in epidemiological studies.

Area of Science:

  • Epidemiology
  • Biostatistics

Background:

  • The ratio of standardized mortality ratios (SMRs) is commonly used but may not provide an unbiased estimate of rate ratios.
  • Unbiasedness is achieved if stratum-specific rates are proportional to the reference population.

Purpose of the Study:

  • To compare the precision and bias of the SMR ratio versus internal (Poisson regression) estimates.
  • To derive expressions for the asymptotic precision of both methods.

Main Methods:

  • Derivation of asymptotic precision formulas for SMR ratio and internal estimates.
  • Analysis of conditions affecting the precision of the SMR ratio.

Main Results:

  • The ratio of SMRs is more precise than internal estimates when data align with proportionality assumptions.
Keywords:
BiasCohort AnalysisComparative StudiesData AdjustmentDemographic FactorsError SourcesEstimation TechnicsEvaluationEvaluation MethodologyMeasurementMethodological StudiesMortalityPopulationPopulation DynamicsResearch MethodologyStandardizationStudiesWorld

Related Experiment Videos

  • Improved precision of the SMR ratio is linked to differences in expected death distributions across strata between cohorts.

    • Conclusions:

    • The choice between SMR ratio and internal estimates involves a trade-off between precision and bias.
    • Understanding the distribution of expected deaths is crucial for optimizing method selection in cohort studies.