Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Autologous gastrointestinal reconstruction

A Bianchi1

  • 1Department of Neonatal and Paediatric Surgery, Royal Manchester Children's Hospital, Pendlebury, England.

Seminars in Pediatric Surgery
|February 1, 1995
PubMed
Summary

Short bowel syndrome (SBS) hinders nutrient absorption due to reduced intestinal surface area or contact time. Autologous gastrointestinal reconstruction (AGIR) surgery offers a promising approach to enhance intestinal adaptation and function.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nitric oxide is involved in the expression of neocortical spike-and-wave spindling episodes in DBA/2J mice.

The Journal of pharmacy and pharmacology·2003
Same author

Delayed presentation of congenital diaphragmatic Bochdalek hernia. Case report.

Minerva pediatrica·2003
Same author

Spectrum of SCN1A mutations in severe myoclonic epilepsy of infancy.

Neurology·2003
Same author

Family study of epilepsy in first degree relatives: data from the Italian Episcreen Study.

Seizure·2003
Same author

Alterations in smooth muscle contractile and cytoskeleton proteins and interstitial cells of Cajal in megacystis microcolon intestinal hypoperistalsis syndrome.

Journal of pediatric surgery·2003
Same author

Evidence for the presence of both peroxisome proliferator-activated receptors alpha and beta in the rat spinal cord.

Journal of chemical neuroanatomy·2003

Area of Science:

  • Gastroenterology and Surgical Innovation

Background:

  • Short bowel syndrome (SBS) results in malabsorption due to diminished mucosal surface area or contact time.
  • Current management relies on parenteral nutrition and optimizing intestinal adaptation.
  • Intestinal failure presents significant challenges in patient care.

Purpose of the Study:

  • To explore surgical interventions for short bowel syndrome.
  • To evaluate the potential of autologous gastrointestinal reconstruction (AGIR) in enhancing intestinal adaptation.
  • To present AGIR as an alternative to intestinal transplantation.

Main Methods:

  • Review of autologous gastrointestinal reconstruction (AGIR) techniques.
  • Analysis of strategies to redistribute residual bowel for enhanced adaptation.
  • Discussion of neomucosal growth potential for increasing absorptive surface.

Main Results:

  • AGIR aims to improve nutrient absorption by optimizing the use of existing bowel.
  • Neomucosal growth may increase the functional absorptive capacity.
  • AGIR offers a potential alternative to intestinal transplantation, avoiding immunosuppression.

Conclusions:

  • Autologous gastrointestinal reconstruction (AGIR) represents an innovative surgical approach for short bowel syndrome.
  • AGIR provides a hopeful alternative for patients with intestinal failure.
  • Further development of AGIR techniques may improve outcomes for SBS patients.

Related Experiment Videos