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Nutrition in the pediatric double lung transplant patient with cystic fibrosis

J A Fulton, D M Orenstein, A N Koehler

    Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
    |April 1, 1995
    PubMed

    Insights

    Nutritional status is critical for pediatric cystic fibrosis (CF) patients post-lung transplant. Gastrostomy tube feeding aids weight gain more effectively than oral intake for improved outcomes in CF patients.

    Area of Science:

    • Pulmonology
    • Genetics
    • Pediatrics

    Background:

    • Cystic fibrosis (CF) is a lethal genetic disease impacting pulmonary and pancreatic function.
    • Malnutrition affects approximately 50% of CF patients, complicating disease management.
    • Nutritional status is crucial for CF patients, especially post-transplant.

    Purpose of the Study:

    • To evaluate the nutritional status of pediatric cystic fibrosis patients after double lung transplantation.
    • To compare weight gain and feeding methods in post-transplant CF patients.

    Main Methods:

    • Retrospective analysis of 10 pediatric CF patients undergoing double lung transplant.
    • Assessment of nutritional status, weight gain, and feeding modalities (gastrostomy tube vs. oral intake).
    • Comparison of outcomes based on survival duration post-transplant.

    Main Results:

    • Patients surviving over 1 year post-transplant showed significantly faster weight gain.
    • Gastrostomy tube feedings were more effective for post-transplant weight gain compared to oral intake.
    • CF patients with pancreatic insufficiency experienced challenges in adjusting immunosuppressive medications.

    Conclusions:

    • Optimizing nutritional status, particularly through gastrostomy tube feeding, is vital for pediatric CF patients after lung transplantation.
    • Further research is needed to understand medication adjustment difficulties in CF patients with pancreatic insufficiency.

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