[Hodgkin's disease: relapse after 16 years of continuous remission]

We report a boy in whom and advanced Hodgkin's disease, nodular sclerosis variety, was diagnosed at 5 years of age and treated with exclusive chemotherapy. After 16 years of remission, he presented with a relapse of the disease, with a different histological pattern and was subjected to chemotherapy (C-MOPP/AVB) and unilateral axillary irradiation, obtaining a complete remission of the disease. Four months later, the patient is asymptomatic and without evidences of relapse.