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Published on: September 22, 2020
Predictors of groin complications after balloon and new-device coronary intervention
R Waksman1, S B King, J S Douglas
1Andreas Gruentzig Cardiovascular Center, Emory University Hospital, Atlanta, Georgia 30322, USA.
Insights
Vascular complications occurred in 6.1% of patients undergoing percutaneous transluminal coronary angioplasty (PTCA). Older age, female gender, and intracoronary stenting were linked to increased complication rates.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Surgery
Background:
- Percutaneous transluminal coronary angioplasty (PTCA) is a common procedure for coronary artery disease.
- Vascular complications at the access site are a known risk of PTCA.
- Newer devices are increasingly used in PTCA, necessitating an understanding of their associated complication rates.
Purpose of the Study:
- To evaluate the incidence and correlates of vascular complications in patients undergoing PTCA.
- To compare complication rates between balloon angioplasty and new devices, including stents, lasers, and atherectomy.
- To identify patient and procedural factors associated with vascular complications requiring intervention.
Main Methods:
- Retrospective review of 5,042 patients undergoing PTCA with balloons or new devices (stent, laser, directional/rotational atherectomy).
- Vascular complications defined as groin hematoma, bleeding, pseudoaneurysm, fistula, or need for surgical repair.
- Statistical analysis to identify correlates of vascular complications.
Main Results:
- Vascular complications occurred in 6.1% of patients (309/5042), with 2.3% (117/5042) requiring vascular repair.
- Pseudoaneurysm repair (72%) was the most common intervention.
- Correlates of complications included older age, female gender, higher weight, higher systolic blood pressure, increased heparin dose, and intracoronary stenting (14.9% vs 3.5%).
Conclusions:
- Vascular complications are a significant concern in PTCA, particularly with intracoronary stenting.
- Patient factors like age and gender, along with procedural anticoagulation, are associated with increased risk.
- The use of devices other than stents did not increase the rate of vascular complications.
Abstract:
We reviewed the clinical course of 5,042 patients who underwent percutaneous transluminal coronary angioplasty (PTCA) using balloons or new devices: (stent, laser, directional and rotational atherectomy). A vascular complication was defined as the formation of a groin hematoma, bleeding, pseudoaneurysm, fistula, or the need for surgical repair. Vascular complications occurred in 309 (6.1%) patients, and 117 (2.3%) required vascular repair; among these patients, surgery was performed for correction of an an arteriovenous fistula in 12%, repair of pseudoaneurysm in 72%, repair for expanding hematoma and femoral artery lacerations in 10%, and retroperitoneal bleeding in 6%. The correlates of vascular complications were older age (66.8 vs 62.1 years; p < 0.0001), female gender (43% vs 26%; p < 0.0001), increased weight (82.1 +/- 16.46 vs 78.0 +/- 16.6 kg; p < 0.001), higher systolic blood pressure (140 +/- 25 vs 134 +/- 20 mm Hg; p < 0.001), increased heparin dose during the procedure (14,352 +/- 3,879 vs 13,599 +/- 3,508 IU; p = 0.001), administration of heparin after the procedure (232 vs 2,985 patients; p < 0.0001) and intracoronary stenting (14.9% vs 3.5%; p < 0.0001). Fifteen patients of 214 (7.0%) who underwent stent implantation had surgical repair. Vascular complications were not related to the size of the arterial sheath (8.11 +/- 0.8 vs 8.8 +/- 0.7Fr; p = 0.11) and the use of devices other than stents (laser, atherectomy) did not increase the rate of vascular complications.
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