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Penicillin-induced lysis of Escherichia coli in medium that does not support sustained growth
Antimicrobial Agents and Chemotherapy
|April 1, 1976
Abstract:
Exponentially growing cells of an Escherichia coli auxotroph that are washed and resuspended in buffer containing a carbon source undergo sufficient growth to render them susceptible to penicillin-induced lysis, even in the absence of the required metabolite. This lysis is probably responsible for the reduction in intracellular enzyme activity previously attributed to a direct effect of penicillin upon the enzyme.
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