Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stress ulcer: is routine prophylaxis necessary?

F Navab1, J Steingrub

  • 1Gastroenterology and Critical Care Division, Baystate Medical Center, Springfield, Massachusetts, USA.

The American Journal of Gastroenterology
|May 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Letter: future directions for epidemiological studies of Barrett's oesophagus.

Alimentary pharmacology & therapeutics·2015
Same author

Letter: is there a relationship between length of Barrett's oesophagus and body mass index?

Alimentary pharmacology & therapeutics·2015
Same author

Patient characteristics and ICU organizational factors that influence frequency of pulmonary artery catheterization.

JAMA·2000
Same author

Liposomal prostaglandin E1 (TLC C-53) in acute respiratory distress syndrome: a controlled, randomized, double-blind, multicenter clinical trial. TLC C-53 ARDS Study Group.

Critical care medicine·1999
Same author

Hemobilia complicating hepatic cryosurgery.

Journal of surgical oncology·1998
Same author

Significance of short-segment Barrett's esophagus.

Journal of clinical gastroenterology·1997

Stress ulcer prophylaxis is not routinely recommended for critically ill patients. Pathogenesis has shifted to gastric ischemia, necessitating a review of bleeding mechanisms and prophylaxis strategies.

Area of Science:

  • Critical care medicine
  • Gastroenterology
  • Pathophysiology

Background:

  • Recent observations challenge the routine use of stress ulcer prophylaxis in critically ill patients.
  • The understanding of stress ulcer pathogenesis has evolved from acid back-diffusion to gastric ischemia.

Purpose of the Study:

  • To review the proposed mechanisms of stress ulcer bleeding.
  • To discuss current prophylaxis strategies in light of new understanding.

Main Methods:

  • Literature review of recent observations and proposed mechanisms.
  • Synthesis of information on stress ulcer pathogenesis and prophylaxis.

Main Results:

  • Stress ulcer bleeding is now understood to be primarily related to gastric ischemia rather than acid back-diffusion.

Related Experiment Videos

  • Routine prophylaxis may not be indicated for all critically ill patients.

    • Conclusions:

    • The shift in understanding necessitates re-evaluation of stress ulcer prophylaxis guidelines.
    • Further research may be needed to refine prophylaxis strategies based on gastric ischemia.