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Primary renal sarcoma

J E Spellman1, D L Driscoll, R P Huben

  • 1Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.

The American Surgeon
|May 1, 1995
PubMed
Summary

Primary renal sarcoma is a rare kidney cancer. Early localized disease offers a better prognosis, while invasive tumors have a poor survival rate.

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Area of Science:

  • Oncology
  • Urology
  • Surgical Pathology

Background:

  • Primary renal sarcoma is a rare kidney tumor, accounting for about 1% of all kidney neoplasms.
  • Sarcomas of the kidney are aggressive malignancies with limited treatment options.

Purpose of the Study:

  • To review the treatment experience for primary renal sarcoma at Roswell Park Cancer Institute.
  • To evaluate the outcomes of patients diagnosed with primary renal sarcoma.

Main Methods:

  • Retrospective review of four patients diagnosed with primary renal sarcoma between 1976 and 1983.
  • All patients underwent radical nephrectomy for tumor removal.

Main Results:

  • Two patients had localized disease, and two had locally invasive tumors.
  • All patients experienced recurrence and metastatic disease.
  • Localized disease recurred at 19 and 25 months; invasive disease recurred at 4 and 5 months.
  • Mean survival for localized disease was 34 months; invasive disease survival was 6 and 10 months.

Conclusions:

  • Primary renal sarcoma is a rare and aggressive malignancy.
  • Localized renal sarcomas have a better prognosis than invasive ones.
  • Early detection and treatment of localized disease are critical for improved patient survival.

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