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Updated: Jul 24, 2026

Measuring Granulocyte and Monocyte Phagocytosis and Oxidative Burst Activity in Human Blood
Published on: September 12, 2016
Exercise, cancer and the immune response of monocytes
C Peters1, H Lötzerich, B Niemeir
1Institute for Rehabilitation and Sports for the Disabled, German Sport University, Cologne, Germany.
Abstract:
We examined the influence of a regularly moderate endurance training program on qualitative and quantitative alterations of monocytes from 24 breast cancer patients. At the beginning, after 5 weeks and 7 months of bicycle training we analyzed the composition of leucocytes and phagocytotic activity of monocytes using two different methods under resting conditions. At the end of the study the amount of granulocytes was enhanced, but lymphocytes and monocytes were decreased. While the phagocytotic capacity of monocytes increased compared with receptor destroying enzyme-treated sheep red blood cells, phagocytosis against Anti D-loaded human erythrocytes did not change. These different results led us to suggest that physical exercise training increases the number of specific receptors in the surface membrane of monocytes.
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