[Characterization of microflora in pyo-destructive lung diseases]

The microflora pattern of the endobronchial secretion was investigated in 74 patients with purulent destructive diseases of the lungs. Specimens of the endobronchial secretion were collected by transtracheal aspiration and bronchoalveolar lavage. The anaerobic isolates were cultivated in anaerostats (OXOID, England) with the use of GasPacks. Bacteriological identification of the pathogens was carried out with respect to 67 patients (90.5 per cent). Non-sporulating anaerobic microflora was isolated from 51 patients (76.1 per cent). Anaerobic causative agents in the patients with complicated pulmonary destructions were detected in 54.3 per cent of the cases. Mono-infection represented by one species of the anaerobes was stated in 23 patients (34.4 per cent). Associations of aerobes and anaerobes were isolated from 28 patients (41.7 per cent). Associations of one strain of the anaerobic causative agents and aerobic microflora were detected in 17 patients (60.7 per cent). In 11 patients the microflora pattern was polymicrobial (89.3 per cent). A total of 66 strains of non-sporulating anaerobic pathogens were isolated. Gram-negative bacilli represented by Prevotella spp., Porphiromonas asaccharolitica and Bacteroides spp. were the most frequent isolates.