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Atomic force microscopy of dimyristoylphosphatidylcholine membranes
1Pharmaceutical Institute, Tohoku University, Sendai, Japan.
Biological & Pharmaceutical Bulletin
|December 1, 1994
Abstract:
We have observed the surface images of dimyristoylphosphatidylcholine (DMPC) monolayer and DMPC vesicles with an atomic force microscope (AFM). It was confirmed that the lattice structure of polar head groups of DMPC molecules in a Langmuir-Blodgett monolayer is similar to those of large unilamellar DMPC vesicles. AFM images of small unilamellar vesicles of DMPC showed larger lattice structures than those of the monolayer, reflecting differences of molecular packing in these membranes.