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The role of tobacco in penile carcinoma
1Department of Genito-urinary Surgery, Cancer Institute (WIA), Adyar, Madras, India.
Objective:
To study the role of tobacco in squamous cell carcinoma of the penis.
Subjects And Methods:
The use of tobacco in the form of cigarettes, chewing tobacco and snuff was studied in a total of 503 patients and age-matched controls.
Results:
By multivariate analysis, a significant association was found between smoking (P = 0.002) or chewing tobacco (P < 0.001) and the use of snuff (P = 0.004) in patients with penile carcinoma as compared with controls. A dose-response relationship was observed for both smoking and chewing.
Conclusions:
The use of tobacco is a significant risk factor for penile carcinoma, and the use of more than one form of tobacco increases this risk.