Related Experiment Videos
Are there ulcerogenic strains of Helicobacter pylori?
1School of Microbiology and Immunology, University of New South Wales, Sydney, Australia.
Aim:
To outline the evidence for and against ulcerogenic strains of Helicobacter pylori.
Controversy:
Although H. pylori is now well established as a predisposing factor in peptic ulcer disease the question of why only a minority of people infected with H. pylori develop peptic ulceration remains unanswered and is the subject of much controversy.
Common View:
Perhaps the most accepted view to date is the belief that there are ulcerogenic strains of H. pylori which produce a specific cytotoxin responsible for the ulceration.
Conclusion:
At the present time the case for ulcerogenic strains is not proven and the differences between H. pylori infected peptic ulcer patients and H. pylori infected non-ulcer subjects may relate simply to host factors.