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Relationship between Helicobacter pylori and atrophic gastritis
European Journal of Gastroenterology & Hepatology
|December 1, 1994
Abstract
Objectives:
To investigate the relationship between Helicobacter pylori and atrophic gastritis.
Design And Methods:
The extent of atrophic gastritis was assessed endoscopically in 97 non-ulcer patients, and their H. pylori status was assessed by enzyme-linked immunosorbent assay.
Results:
The prevalence of H. pylori infection was greatest in the early stages of atrophic gastritis. Small numbers of H. pylori-negative patients were identified at different stages during the extension of atrophic gastritis.
Conclusions:
H. pylori infection precedes the extension of atrophic gastritis, and a minority of patients with atrophic gastritis may never have been infected with H. pylori.