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The kinase insert domain receptor gene (KDR) has been relocated to chromosome 4q11-->q12
S N Sait1, M Dougher-Vermazen, T B Shows
1Department of Human Genetics, Roswell Park Cancer Institute, Buffalo NY.
Cytogenetics and Cell Genetics
|January 1, 1995
Abstract:
Through in situ hybridization of a genomic DNA probe to metaphase chromosomes, we have localized the KDR gene to 4q11-->q12. This is the same locus as that for two other receptor tyrosine kinases, PDGFRA and KIT. This location for KDR differs from that which we previously reported using a cDNA probe. Using cDNA probes for both KDR and KIT identifies a locus at 4q31-->q32 which may uncover another cluster of receptor tyrosine kinase genes.