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A microdissection library of the rat renal carcinoma gene region
D W Bell1, R S Yeung, S K Bohlander
1Division of Medical Sciences, Fox Chase Cancer Center, Philadelphia, PA, USA.
Cytogenetics and Cell Genetics
|January 1, 1995
Abstract:
Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequences in the vicinity of this locus following the microdissection, construction and characterization of a region-specific DNA library for rat chromosome band 10q12.