Muscle lines-of-action affect predicted forces in optimization-based spine muscle modeling

This study describes the effects of varied torso muscle geometries commonly assumed in optimization-based muscle force prediction models. Specifically, the sensitivity of predicted muscle and spinal forces to assumed muscle lines-of-action (LOA) is systematically examined. The practical significance of varied muscle LOAs is addressed by determining the relative precision needed for individual muscle LOAs and assessing which muscles are more critical to accurate prediction of spinal forces. To perform this analysis a nonlinear optimization model was used to generate muscle force predictions during combined frontal and sagittal plane moment loadings with an assumed erect posture. The LOAs of the erector spinae, rectus abdominus, internal and external oblique, and latissimus dorsi were systematically varied in the frontal and sagittal planes over an anatomically feasible range. The results indicated that moderate changes in the assumed LOA could substantially alter the magnitudes of predicted muscle and spinal forces. The estimated activity level of a muscle, as well as the predicted active/silent state could be affected by the LOA of that muscle and others. The patterns of predicted muscle activity, with respect to load orientation, underwent only minor alterations with changing LOA. The relative activation of several muscles, however, was dependent on LOA, and frequently led to variations in predicted spinal compression (> 100 N change) and shear forces (> 50 N change). This dependence of estimated spinal forces on assumed muscle geometry was most pronounced for the obliques and minimal for the more vertically oriented muscles and when loads were sagittally symmetric. This study suggests that muscle LOAs are critical inputs when interpreting absolute muscle and spinal force values predicted by models of physical exertions.