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Updated: Aug 13, 2026
17:13
Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET
Published on: April 28, 2013
Diffuse renal retention on bone scintigraphy in localized clear-cell renal epithelial neoplasm
1Nuclear Medicine Section, Department of Veterans Affairs Medical Center, Seattle, Washington 98108, USA.
Summary
Bone scintigraphy detected abnormal kidney retention, leading to the discovery of a small, non-malignant clear-cell neoplasm. This finding highlights the importance of investigating unexpected imaging results for potential renal masses.
Area of Science:
- Nephrology
- Radiology
- Oncology
Background:
- Incidental sclerotic rib lesion on chest radiograph prompted bone scintigraphy.
- Bone scintigraphy revealed unexpected diffuse parenchymal retention in the left kidney.
Observation:
- Renal ultrasound identified an ovoid, hyperechoic mass in the left kidney's inferior pole.
- Contrast-enhanced CT confirmed a well-circumscribed, hypervascular renal mass.
Findings:
- Nephrectomy identified a 1.5-cm clear-cell epithelial neoplasm, not definitively malignant.
- No metastatic disease was evident from bone scintigraphy.
- The renal mass was not associated with calcifications or parenchymal changes explaining the bone agent retention.
Implications:
- Hyperemia associated with the renal neoplasm may explain the bone-seeking agent retention.
- Further investigation is warranted for unexplained renal parenchymal retention on bone scintigraphy.
- Highlights the diagnostic utility of multimodal imaging in evaluating incidental findings.
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