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[Disseminated intravascular coagulation associated with prostatic cancer]
La Revue De Medecine Interne
|January 1, 1995
Summary
Disseminated intravascular coagulation (DIC) in prostate cancer patients indicates a poor prognosis. This rare complication, characterized by low platelets and coagulation factors, often presents with bleeding and has limited treatment options.
Area of Science:
- Oncology
- Hematology
Context:
- Prostate adenocarcinoma is a common cancer in elderly men.
- Disseminated intravascular coagulation (DIC) is a rare but serious complication of various cancers.
- DIC associated with prostate cancer signifies a poor prognosis.
Purpose:
- To report four cases of prostate adenocarcinoma presenting with disseminated intravascular coagulation (DIC).
- To review the literature on DIC in prostate cancer.
- To highlight the clinical features, treatment, and outcomes of this rare complication.
Summary:
- Four elderly male patients with prostate adenocarcinoma and DIC were identified.
- Clinical presentation included low platelet counts and coagulation factors, with bleeding complications in two cases leading to cancer diagnosis.
- Standard treatments (hormonotherapy and heparin) showed limited efficacy, with short remissions followed by fatal outcomes.
Impact:
- This study underscores the poor prognosis associated with DIC in prostate cancer.
- It highlights the diagnostic challenges and limited therapeutic options currently available.
- The findings emphasize the urgent need for novel treatment strategies for this ominous complication.