Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lung ultrasound is a promising screening tool to rule out interstitial lung disease in patients with rheumatoid arthritis.

Respirology (Carlton, Vic.)·2024
Same author

Nonscarring Alopecia Secondary to Secukinumab.

Actas dermo-sifiliograficas·2022
Same author

Nonscarring Alopecia Secondary to Secukinumab.

Actas dermo-sifiliograficas·2022
Same author

Anti-citrullinated protein antibodies and arthritis in Sjögren's syndrome: a systematic review and meta-analysis.

Scandinavian journal of rheumatology·2018
Same author

A case series describing common radiographic and pathologic patterns of hard metal pneumoconiosis.

Respiratory medicine case reports·2018
Same author

Evaluation of learned helplessness, self-efficacy and disease activity, functional capacity and pain in Argentinian patients with rheumatoid arthritis.

Scandinavian journal of rheumatology·2016

Related Experiment Video

Updated: Jul 26, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Pulmonary involvement in rheumatoid arthritis

J M Anaya1, L Diethelm, L A Ortiz

  • 1Department of Medicine, Louisiana State University School of Medicine, New Orleans, USA.

Seminars in Arthritis and Rheumatism
|February 1, 1995
PubMed
Summary

Rheumatoid arthritis (RA) can affect the lungs, causing conditions like pleurisy and fibrosis. Treatment for RA-related lung disease is empirical, often involving corticosteroids and immunosuppressants.

More Related Videos

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
10:39

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding

Published on: August 30, 2024

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

Related Experiment Videos

Last Updated: Jul 26, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
10:39

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding

Published on: August 30, 2024

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

Area of Science:

  • Rheumatology
  • Pulmonology
  • Immunology

Background:

  • Rheumatoid arthritis (RA) is a systemic autoimmune disease primarily affecting joints but also manifesting as extra-articular disease.
  • Pulmonary involvement is a significant extra-articular manifestation of RA, encompassing various conditions affecting the lungs.
  • While RA is more prevalent in women, rheumatoid lung disease disproportionately affects men with long-standing disease, positive rheumatoid factor, and nodules.

Purpose of the Study:

  • To summarize the spectrum of pulmonary involvement in rheumatoid arthritis.
  • To describe the clinical features, histology, and treatment of various rheumatoid lung diseases.
  • To highlight the challenges in diagnosing and managing lung complications in RA patients.

Main Methods:

  • Review of existing literature on pulmonary manifestations of rheumatoid arthritis.
  • Analysis of clinical presentations, diagnostic criteria, and treatment outcomes.
  • Discussion of specific lung conditions associated with RA, including interstitial lung disease, airway disease, and drug-induced pneumonitis.

Main Results:

  • Pleural involvement is the most common lung manifestation in RA, often asymptomatic.
  • Pulmonary fibrosis in RA shares similarities with idiopathic pulmonary fibrosis.
  • Bronchiolitis obliterans organizing pneumonia (BOOP), obliterative bronchiolitis (OB), and methotrexate (MTX)-pneumonitis are recognized pulmonary complications.
  • Rheumatoid pulmonary vasculitis is rare.
  • Pulmonary disease can also be a toxic effect of RA treatments.

Conclusions:

  • Pulmonary involvement in RA is diverse and requires careful diagnosis and management.
  • Treatment strategies for rheumatoid lung disease are often empirical, focusing on corticosteroids and immunosuppressants.
  • Early recognition and intervention are crucial for managing lung complications in RA patients.