Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Improvement from multiple tics after dexamphetamine]

N Hansen1

  • 1Psykiatrisk Børnehospital, Risskov.

Ugeskrift for Laeger
|April 3, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SMAS: Structural MRI-based AD Score using Bayesian supervised VAE.

Computers in biology and medicine·2025
Same author

Gaussian Process-based prediction of memory performance and biomarker status in ageing and Alzheimer's disease-A systematic model evaluation.

Medical image analysis·2023
Same author

Molecular-Weight Growth in Ozone-Initiated Low-Temperature Oxidation of Methyl Crotonate.

The journal of physical chemistry. A·2020
Same author

Process and Outcome Evaluation of a Mindfulness-Based Cognitive Therapy Intervention for Cisgender and Transgender African American Women Living with HIV/AIDS.

AIDS and behavior·2020
Same author

Diagonal Acceleration for Covariance Matrix Adaptation Evolution Strategies.

Evolutionary computation·2019
Same author

Detection of Aliphatically Bridged Multi-Core Polycyclic Aromatic Hydrocarbons in Sooting Flames with Atmospheric-Sampling High-Resolution Tandem Mass Spectrometry.

The journal of physical chemistry. A·2018
Same journal

[Mosaicism as a cause of Cowden syndrome].

Ugeskrift for laeger·2026
Same journal

[Thyrotoxic crisis with cardiogenic shock].

Ugeskrift for laeger·2026
Same journal

[Mindfulness-based cognitive therapy in the treatment of depression].

Ugeskrift for laeger·2026
Same journal

[Fitness].

Ugeskrift for laeger·2026
Same journal

[Risk of developing cataract related to fluoroscopy].

Ugeskrift for laeger·2026
Same journal

[Obturator hernia with small bowel ileus presenting as hip pain in an elderly woman].

Ugeskrift for laeger·2026
See all related articles

Multiple tics in a pubertal child improved with dexamphetamine after neuroleptic withdrawal, challenging the view of tics as a purely neuro-organic hyperdopaminergic condition.

Area of Science:

  • Neuroscience
  • Child Psychiatry
  • Pharmacology

Background:

  • Investigating the neurobiological underpinnings of complex behavioral disorders in children.
  • Understanding the role of dopaminergic pathways in conditions like tics, attention deficits, and conduct disorder.

Observation:

  • A case study of a pubertal child presenting with multiple tics, concentration difficulties, and conduct disorder.
  • Observed a paradoxical improvement in tics following the discontinuation of neuroleptic medication.
  • Noted a significant reduction in tic severity upon introduction and dose escalation of dexamphetamine.

Findings:

  • The patient's multiple tics showed improvement when neuroleptics were stopped and dexamphetamine was administered.
  • This clinical course suggests that tics may not solely be a hyperdopaminergic neuro-organic disease.

Related Experiment Videos

  • Dexamphetamine's efficacy in this case warrants further investigation into its therapeutic potential for tic disorders.

    • Implications:

    • Challenges the established neuro-organic hyperdopaminergic model for all cases of multiple tics.
    • Suggests a potential role for dopaminergic modulation, possibly via stimulants like dexamphetamine, in managing complex tic disorders.
    • Highlights the need for individualized treatment approaches in pediatric behavioral and neurological conditions.