Adult renal epithelial neoplasms

The consideration of adult renal epithelial neoplasms is no longer limited to renal adenocarcinoma, but also includes oncocytoma, chromophobe carcinoma, renal papillary neoplasms, collecting duct carcinoma, and neuroendocrine tumors. The recent application of classical and molecular cytogenetic techniques, particularly the studies of Kovacs and colleagues, has provided a biologic basis for this new classification. This review discusses the clinical and pathologic characteristics of these entities, with attention to differential diagnosis. Prognostic factors in renal adenocarcinoma are also discussed.