Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Randomised trial spacer v nebuliser for acute asthma

P C Parkin1, N R Saunders, S A Diamond

  • 1Division of General Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.

Archives of Disease in Childhood
|March 1, 1995
PubMed
Summary

For young children hospitalized with asthma, a spacer device is as effective as a nebulizer for treatment delivery. This study found no significant differences in clinical scores between the two methods in pediatric asthma patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between maternal schizophrenia and risk of serious asthma exacerbations in childhood.

Schizophrenia research·2024
Same author

Urinary incontinence, faecal incontinence and pelvic organ prolapse symptoms 20-26 years after childbirth: A longitudinal cohort study.

BJOG : an international journal of obstetrics and gynaecology·2024
Same author

Breakthrough COVID-19 is mild in vaccinated patients with hematological malignancy receiving tixagevimab-cilgavimab as pre-exposure prophylaxis.

Leukemia & lymphoma·2023
Same author

Trends in child pedestrian motor vehicle collision injury rates by neighborhood deprivation score in Toronto, Canada.

Preventive medicine reports·2022
Same author

Antenatal preventative pelvic floor muscle exercise intervention led by midwives to reduce postnatal urinary incontinence (APPEAL): protocol for a feasibility and pilot cluster randomised controlled trial.

Pilot and feasibility studies·2022
Same author

Complex chronic conditions among children born to women with schizophrenia.

Schizophrenia research·2022

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Clinical Therapeutics

Background:

  • Asthma is a common chronic respiratory disease in children.
  • Effective medication delivery is crucial for managing pediatric asthma exacerbations.
  • Nebulizers have traditionally been used, but inhaler-based devices with spacers are alternatives.

Purpose of the Study:

  • To compare the efficacy of a spacer versus a nebulizer for delivering asthma medication in hospitalized children aged 1-5 years.
  • To evaluate clinical outcomes and secondary measures in young asthmatic patients receiving different delivery methods.

Main Methods:

  • Randomized controlled trial involving sixty hospitalized children with asthma (age 1-5 years).
  • Participants were assigned to either a spacer or a nebulizer group.

Related Experiment Videos

  • Clinical scores were assessed at baseline and every 12 hours to monitor treatment response.

    • Main Results:

    • No statistically significant differences were observed in the clinical scores between the spacer and nebulizer groups over time.
    • Secondary outcome measures also showed no significant variations between the two treatment arms.
    • Both delivery methods demonstrated comparable effectiveness in this pediatric population.

    Conclusions:

    • Spacer devices are an effective and viable alternative to nebulizers for delivering asthma medications to young, hospitalized children.
    • The findings support the use of spacers in pediatric asthma care, potentially offering advantages in certain clinical settings.
    • Further research may explore patient comfort and cost-effectiveness of each method.