Related Experiment Video
Updated: Jan 10, 2026

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
Heparin-rebound in the early postoperative phase following cardiopulmonary bypass
P Subramaniam1, P Skillington, J Tatoulis
1Cardiothoracic Unit, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Abstract:
The incidence of the 'heparin-rebound' phenomenon after protamine neutralization of systemic heparinization required for cardiopulmonary bypass (CPB) was investigated. Heparin-effect was detected in 43% of patients studied at 2 h, 31% at 4 h, and 37% at 8 h after reversal of circuit heparin on CPB. Heparin-rebound was shown to be associated with a small but significant increase in postoperative bleeding which was not of clinical importance.
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Peripheral Artery Disease V: Postoperative Nursing Management
Cardiac Catheterization IV: Nursing Management
Cardiac Catheterization II: Right Heart Catheterization
Cardiac Catheterization I: Pre-Procedure Overview
Anticoagulant Drugs: Low-Molecular-Weight Heparins

