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Highly conserved genes coding for eukaryotic translation initiation factor eIF-4A of tobacco have specific
K A Brander1, T Mandel, G W Owttrim
1Institute of Plant Physiology, University of Berne, Altenbergrain, Switzerland.
Biochimica Et Biophysica Acta
|April 26, 1995
Abstract:
Eukaryotic translation initiation factor eIF-4A is an ATP-dependent RNA helicase that is required for the binding of mRNA to ribosomes. Plant eIF-4A-like proteins are highly homologous to eIF-4As from yeast, mouse and Drosophila melanogaster. The pattern of intron-exon boundaries in eIF-4A-like genes are conserved within tobacco, but are not conserved with other organisms. Fixed spacings between the functionally important sequence motifs, GKT-PTRELA (72 bp), DEAD-SAT (81 bp) and SAT-HRIGR (426 bp), are conserved between plants, mouse, Drosophila and yeast.