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Updated: Aug 31, 2026

A Method of Nodose Ganglia Injection in Sprague-Dawley Rat
Published on: November 25, 2014
[Biological characteristics of neurons of dorsal vagal nucleus]
Abstract:
Stereological, histochemical, and electron microscopic approaches were applied to study the cellular and synaptic structure of the rat dorsal vagal nucleus (DVN). The cellular organization of the DNV does not allow one to distinguish any subnuclei, but the conspicious population of mostly small neurons in the lateral nucleus' rostral stretch lacking AChE activity. DVN neurons with high and moderate AChE activities were evident on the 5th postnatal day. Their number increased on day 7. In this critical period of brain sex differentiation, sex dimorphism was observed in the activity of DVN cholinergic neurons. Electron microscopic studies showed a great variety of DVN patterns. The fact that in the rat DVN there are complicated synaptic structures resembling glomerules is described in the paper. Two types of synaptic glomerules were identified. The results suggest that DVN can be seen as a sex-dependent brain region involved in sufficiently high information processing.
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