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Bleeding time in normal children

L A Aversa1, A Vázquez, J A Peñalver

  • 1Unidad Hematología, Hospital de Niños Dr. Ricardo Gutiérrez, Buenos Aires, Argentina.

Journal of Pediatric Hematology/Oncology
|February 1, 1995
PubMed
Summary
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Pediatric bleeding times (BTs) are significantly shorter than adult BTs. New reference ranges for children are proposed, aiding clinical diagnosis and interpretation in pediatric hematology.

Area of Science:

  • Pediatric Hematology
  • Clinical Pathology

Background:

  • Limited data exists on normal bleeding times (BTs) in pediatric populations.
  • Accurate BT reference ranges are crucial for diagnosing hemostatic disorders in children.

Purpose of the Study:

  • To establish reference values for bleeding times in children across different age groups.
  • To compare pediatric BTs with those of adult volunteers.

Main Methods:

  • Bleeding times were measured in normal children (four age groups) and adult volunteers using a Simplate device with a vertical forearm incision.
  • Data was analyzed to compare BTs between pediatric age groups, sexes, and adults.

Main Results:

  • Children exhibited significantly shorter mean bleeding times (270 s, 95th percentile 420 s) compared to adults (320 s, 95th percentile 480 s; p = 0.001).

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  • While variations existed across pediatric age groups and sexes, only adult sex showed a statistically significant difference.

    • Conclusions:

    • Recommended reference values for children: 0-4 years (4 ± 1 min), boys > 4 years (5 ± 1 min), and girls > 4 years (5.5 ± 1 min).
    • Pediatric bleeding times are demonstrably shorter than adult values, necessitating age-specific reference ranges for accurate clinical assessment.