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Updated: Aug 23, 2026

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Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
On the location of the cone and the etiology of keratoconus
1Boston Eye Associates, Chestnut Hill, Massachusetts 02167-2115, USA.
Cornea
|March 1, 1995
Abstract:
I suggest that the location of the cone in keratoconus is most often located in the paracentral inferonasal quadrant of the cornea due to the presence of the most senile epithelial cells in this location. These cells may be more vulnerable than younger epithelial cells to the chronic subtle trauma of eyelid rubbing and may be more prone to release enzymes that thin the cornea.
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