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Renal aspergillosis and AIDS
J Martinez-Jabaloyas1, J M Osca, J L Ruiz
1Department of Urology, La Fe Hospital, Valencia, Spain.
Abstract:
Primary renal aspergillosis is an extremely rare entity. Only 19 cases have been reported, 3 of them in patients with AIDS. We report one new case of renal aspergillosis in a patient with AIDS. His disease pattern was multiple bilateral renal abscesses with a normal excretory pathway. The treatment established was percutaneous drainage and systemic antifungal drugs. He had a bad evolution and died 14 weeks after diagnosis. In the previously reported cases of aspergillosis in patients with AIDS, the manifestation was unilateral renal abscess.
Insights
Primary renal aspergillosis is rare, especially in patients with Acquired Immunodeficiency Syndrome (AIDS). This case highlights a rare bilateral presentation in an AIDS patient, emphasizing the need for effective treatment strategies for this severe fungal infection.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Nephrology
Background:
- Primary renal aspergillosis is an exceptionally rare fungal infection affecting the kidneys.
- Fewer than 20 cases have been documented globally, with only three occurring in individuals with Acquired Immunodeficiency Syndrome (AIDS).
- Previous reports in AIDS patients typically described unilateral renal abscesses.
Observation:
- A new case of primary renal aspergillosis is presented in a patient diagnosed with AIDS.
- The patient exhibited a unique pattern of multiple bilateral renal abscesses.
- The excretory pathway of the kidneys remained functionally normal despite the abscesses.
Findings:
- The patient was treated with percutaneous drainage and systemic antifungal medications.
- Despite treatment, the patient experienced a poor clinical outcome.
- The patient succumbed to the infection 14 weeks following the diagnosis.
Implications:
- This case expands the known spectrum of renal aspergillosis presentation in AIDS patients, now including bilateral involvement.
- The aggressive progression and poor outcome underscore the challenges in managing invasive fungal infections in immunocompromised individuals.
- Further research into optimal therapeutic approaches for renal aspergillosis in the context of AIDS is warranted.