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[Acute complications in full term neonates with severe neonatal asphyxia]
C Aldana Valenzuela1, S Romaro Maldonado, A Vargas Origel
1Hospital de Ginecopediatría No. 48 Centro Médico Nacional, Instituto Mexicano del Seguro Social, Leon, Gto.
Ginecologia Y Obstetricia De Mexico
|March 1, 1995
Summary
Perinatal asphyxia, a condition with low umbilical artery pH, led to significant systemic complications in newborns, including organ dysfunction and high mortality. Apgar scores did not correlate with cord pH, highlighting limitations in assessing asphyxia severity.
Area of Science:
- Neonatal Medicine
- Perinatal Health
- Pediatric Complications
Context:
- Perinatal asphyxia is a critical condition in newborns, defined by low umbilical artery pH (≤7.10).
- Evaluating acute systemic complications and associated prenatal factors is crucial for understanding neonatal outcomes.
- This study focuses on fifty full-term newborns experiencing perinatal asphyxia.
Purpose:
- To evaluate the acute systemic complications of perinatal asphyxia in full-term newborns.
- To investigate prenatal factors contributing to asphyxia and its relationship with Apgar scores and cord pH.
Summary:
- The study identified significant systemic complications in newborns with perinatal asphyxia, including renal, brain, and myocardial dysfunction, as well as severe respiratory disease.
- Hypocalcemia was the most frequent metabolic complication (44%).
- A notable finding was the lack of correlation between Apgar scores and cord pH, and a high mortality rate of 22%, with Persistent Pulmonary Hypertension as the primary cause of death.
Impact:
- Findings underscore the severity of perinatal asphyxia and its wide-ranging systemic effects on neonates.
- The lack of Apgar score-pH correlation suggests a need for improved methods to assess asphyxia severity at birth.
- Identifying prolonged labor and abruptio placentae as common associated conditions can inform preventative strategies and clinical management.